Stepwise covariate modeling with nlmixr2scm
Watch on YouTube nlmixr2scm is on CRAN! Happily, nlmixr2scm, which does stepwise covariate modeling (SCM) for nlmixr2 models, is now on CRAN. It took a while - seems they’re very busy now that everyone is churning out packages with AI - but it’s finally there. install.packages("nlmixr2scm") If you’ve built covariate models in NONMEM, you’ve probably used scm in Perl-speaks-NONMEM. nlmixr2scm follows the same approach (Jonsson & Karlsson, 1998), and it works directly on an nlmixr2 fit.